Chemical changes happen on a much smaller scale. While some experiments show obvious chemical changes such as a color change, most chemical changes happen between molecules and are unseen. When iron (Fe) rusts you can see it happen over a long period of time. The actual molecules have changed their structure (the iron oxidized). Melting a sugar cube is a physical change because the substance is still sugar. Burning a sugar cube is a chemical change. The energy of the fire has broken down the chemical bonds.
Some changes are extremely small. Chemical changes can happen over a series of steps, and the result might have the same number of atoms but have a different structure. The sugars glucose, galactose, and fructose all have six carbon atoms, twelve hydrogen atoms, and six oxygen atoms. Even though they are made of the same atoms, they have very different shapes and are called structural isomers. They each have different chemical reactions because of their molecular structure.
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